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Afatinib

●Purchase●DescriptionAfatinib,alsoknownasBIW-2992,isanirreversibledualinhibitorofepidermalgrowthfactorreceptor1(EGFR)and2(HER2)tyrosinekinases

  • 产品型号:27009
  • 厂商性质:生产厂家
  • 更新时间:2024-02-05
  • 访  问  量:122
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Description

Afatinib, also known as BIW-2992, is an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinases. Afatinib suppresses EGF-induced EGFR phosphorylation and cellular proliferation in various cell lines, including EGFR-overexpressing and HER2-expressing cell lines A431, NIH-3T3-HER2, NCI-N87 and BT-474.

Synonyms
BIW-2992
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