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●Purchase●DescriptionLDN-57444isacellpermeableubiquitinC-terminalhydrolase(UCH-L1)inhibitor(Ki=0
产品型号:27706-2
厂商性质:生产厂家
更新时间:2023-12-19
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LDN-57444 is a cell permeable ubiquitin C-terminal hydrolase (UCH-L1) inhibitor (Ki=0.4 μM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis and causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. LDN-57444 is a useful tool to study UCH-L1 in different pathological conditions such as cancer and neurodegeneration.