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●Purchase●DescriptionMocetinostatselectivelyinhibitshistonedeacetylases(HDACs)1-3and11atsubmicromolarconcentrations
产品型号:27019
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更新时间:2023-12-19
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Mocetinostat selectively inhibits histone deacetylases (HDACs) 1-3 and 11 at submicromolar concentrations. It blocks cancer cell proliferation in vitro and has significant antitumor activity in vivo. Mocetinostat induces hyperacetylation of histones, causes expression of the tumor suppressor protein p21(WAF1/CIP1), and inhibits proliferation of human cancer cells growing in culture.
