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Spike Trimer (S1+S2) (B.1.351, Beta Variant, Δ242-244) (SARS-CoV-2) Recombinant

●Purchase●DescriptionRecombinantSARS-CoV-2Spikeproteininitshomotrimericform,containingS1+S2subunitsandencompassingaminoacids16-1213

  • 产品型号:101091
  • 厂商性质:生产厂家
  • 更新时间:2024-02-10
  • 访  问  量:140
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Description

Recombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein corresponds to SARS-CoV-2 Variant B.1.351, also known as variant Beta originally discovered in South Africa, and contains the nine known mutations listed below, in addition to deletion 242-244*. The construct also contains mutations 682RRAR685>A, K986P and V987P, and a T4 trimerization domain followed by a His-tag (6xHis) in C-terminal. The recombinant protein was affinity purified.

*Deletion 242-244 is known as 241-243 in some databases and on the CDC website. This is the same deletion. As stated by Tegally et al., Nature 2021: "We also observe a deletion of three amino acids at positions 242 to 244, which was seen in samples extracted and generated in different laboratories across the NGS-SA. This region is difficult to align; the deletion could potentially also be located at positions 241 to 243, but the resulting sequence would be exactly the same. "

This product has been cited 3 times.

Synonyms
20H/501Y.V2, sars cov 2 Spike Trimer, South African Variant
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