热门搜索: 50072ATAT1, GST-tag Recombinant 40520ATF2, GST-Tag Recombinant 31114GCN5 (727-837), His-tag Recombinant 50074GCN5 (KAT2A), FLAG-tag Recombinant 50071p300 (KAT3B), His-GST-tag Recombinant 11004ACHE, His-Tag Recombinant 50272BCL-2, His-Tag Recombinant 100077BCL2A1, His-Tag Recombinant 100080BCL2L10, His-Tag Recombinant 100091BCL2L2, His-Tag Recombinant 80113Caspase6, His-tag Recombinant 70000Caspase7, His-tag Recombinant 80114Caspase8, His-tag Recombinant 100543GPX4, FLAG-Tag Recombinant 100054MALT1, FLAG-Tag (Mouse) Recombinant 100637MCL-1 His-Tag (Mouse) Recombinant

PRODUCT CLASSIFICATION

产品分类

TECHNICAL ARTICLES

相关文章

产品展示/ Product display

您的位置:首页  /  产品展示  /    /  Kinase  /  78316BRAF (WT) Kinase Assay Kit

BRAF (WT) Kinase Assay Kit

●Purchase●DescriptionBRAFisaserine-threoninekinaseactivatedbytheRASGTPasesinresponsetogrowthfactorstimulationoroncogenicinsult

  • 产品型号:78316
  • 厂商性质:生产厂家
  • 更新时间:2024-01-31
  • 访  问  量:112
立即咨询

联系电话:13829799985

详细介绍
Purchase
Description

BRAF is a serine-threonine kinase activated by the RAS GTPases in response to growth factor stimulation or oncogenic insult. Upon stimulation, BRAF phosphorylates the kinase MEK1 (dual specificity mitogen-activated protein kinase kinase 1), resulting in the activation of the MAP-kinase (mitogen-activated protein) cascade. The MAP-kinase signaling pathway controls cell growth, and dysregulation of this pathway is frequently observed in cancer. Inherited BRAF mutations cause birth defects, while cancer-associated mutations are frequently observed in melanoma. BRAF is a validated therapeutic target for anti-cancer drugs, notably in melanoma. The BRAF (WT) Kinase Assay Kit is designed to measure BRAF(WT) kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.

Synonyms
BRAF1, RAFB1, B-raf 1, MGC126806, MGC138284, BRAF kit
留言询价

留言框

  • 产品:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 省份:

  • 详细地址:

  • 补充说明:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7
关注公众号

邮箱:infocn@bpsbioscience.com

传真:

地址:上海静安区

Copyright © 2024 BPS Bioscience Inc.版权所有   备案号:   技术支持:化工仪器网

TEL:13829799985

扫码加微信