TTK (MPS-1) Kinase Assay Kit

TTK, also known as Monopolar Spindle 1 Kinase (MPS-1), is a dual specific kinase (tyrosine and serine/threonine) that plays an important role in the cell division cycle by regulating spindle assembly checkpoint during mitosis. Recent studies showed that inhibition of TTK induces aberrant mitosis and apoptosis in various cancer cells, suggesting that TTK is a potential cancer therapeutic target. The TTK Kinase Assay Kit is designed to measure TTK kinase activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent.